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Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.

What will be her last straw? A devastatingly bad day pushes a hardworking single mother to the breaking point — and into a shocking act of desperation.

Keller Dover is facing every parent’s worst nightmare. His six-year-old daughter, Anna, is missing, together with her young friend, Joy, and as minutes turn to hours, panic sets in. The only lead is a dilapidated RV that had earlier been parked on their street.

A mathematical genius discovers a link between numbers and reality, and thus believes he can predict the future.

The story of American showman P.T. Barnum, founder of the circus that became the famous traveling Ringling Bros. and Barnum & Bailey Circus.

Dr. Steven Murphy is a renowned cardiovascular surgeon who presides over a spotless household with his wife and two children. Lurking at the margins of his idyllic suburban existence is Martin, a fatherless teen who insinuates himself into the doctor's life in gradually unsettling ways.

A man has only three and a half days and limited resources to discover why he was imprisoned in a nondescript room for 20 years without any explanation.

Chris and his girlfriend Rose go upstate to visit her parents for the weekend. At first, Chris reads the family's overly accommodating behavior as nervous attempts to deal with their daughter's interracial relationship, but as the weekend progresses, a series of increasingly disturbing discoveries lead him to a truth that he never could have imagined.

Leonard Shelby is tracking down the man who raped and murdered his wife. The difficulty of locating his wife's killer, however, is compounded by the fact that he suffers from a rare, untreatable form of short-term memory loss. Although he can recall details of life before his accident, Leonard cannot remember what happened fifteen minutes ago, where he's going, or why.

Susan Morrow receives a book manuscript from her ex-husband – a man she left 20 years earlier – asking for her opinion of his writing. As she reads, she is drawn into the fictional life of Tony Hastings, a mathematics professor whose family vacation turns violent.

Frederick Abberline is an opium-huffing inspector from Scotland Yard who falls for one of Jack the Ripper's prostitute targets in this Hughes brothers adaption of a graphic novel that posits the Ripper's true identity.

With the help of a German bounty hunter, a freed slave sets out to rescue his wife from a brutal Mississippi plantation owner.

When athletic teen Mari Collingwood opts to hang out with her friend Paige in town rather than spend an evening in with her parents vacationing at the family's remote lake house, it marks the beginning of a night no one is going to forget.

Terrence McDonagh is a New Orleans Police sergeant, who receives a medal and a promotion to lieutenant for heroism during Hurricane Katrina. Due to his heroic act, McDonagh injures his back and becomes addicted to prescription pain medication. He then finds himself involved with a drug dealer who is suspected of murdering a family of African immigrants.

In the land of Oz, ostracized and misunderstood green-skinned Elphaba is forced to share a room with the popular aristocrat Glinda at Shiz University, and the two's unlikely friendship is tested as they begin to fulfill their respective destinies as Glinda the Good and the Wicked Witch of the West.