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Splice

Splice

She's not human...not entirely.

20105.91h 44m

Overview

Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Directed by Vincenzo Natali
Written by Antoinette Terry Bryant, Vincenzo Natali, Doug Taylor
Produced by Steven Hoban, Guillermo del Toro, Franck Chorot
Box OfficeBudget: $26.0M0

Top Cast

Adrien Brody

Adrien Brody

Clive

Sarah Polley

Sarah Polley

Elsa

Delphine Chanéac

Delphine Chanéac

Dren

David Hewlett

David Hewlett

Barlow

Abigail Chu

Abigail Chu

Young Dren

Stephanie Baird

Stephanie Baird

Elsa / PD

Brandon McGibbon

Brandon McGibbon

Gavin

Amanda Brugel

Amanda Brugel

Melinda Finch

Simona Măicănescu

Simona Măicănescu

Joan Chorot

Themes & Keywords

experimentgeneticsdnagene manipulationgenetic engineeringdisturbedgrimgenetically modified organismabsurddisgusteddistressing

About Splice

Splice is a horror, science fiction film released in 2010 exploring themes of experiment, genetics, dna, gene manipulation, genetic engineering, disturbed. Directed by Vincenzo Natali, it stars Adrien Brody, Sarah Polley, Delphine Chanéac. Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named "Dren", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.

Movies Similar to Splice

Discover titles like Splice — ranked by similarity and community votes

We found 15 movies similar to Splice

If you enjoyed Splice, you'll love these handpicked recommendations. Each title below shares similar themes, tone, and storytelling style. Our algorithm analyzes genres, keywords, director filmography, and cast connections to find the closest matches. Whether you're looking for the same emotional depth, narrative structure, or visual style, these picks are curated to deliver the best viewing experience for fans of Splice.

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